ABOUT US

Introduction

Overview

Founded in 2016, Chongqing Precision Biotech Co., Ltd. is a high-tech enterprise jointly established by a technical team which leaded by famous precision medicine scientist Professor Qian Cheng and Chongqing Zhifei Biological Products Co., Ltd. (also known as Zhirui Investment). Taking cell therapy technology research as its starting point, Chongqing Precision engaged in the development and application of gene and cell drugs, and is determined to become a global, innovative and pioneering biomedical enterprise.

Adhering to the core concept of "keep improving and be meticulous", we focus on scientific research and continuously innovates. As of April 2023, we established R&D cooperation and expert exchange mechanisms with 7 overseas institutes and 19 domestic universities, bringing together more than 20 experts and scholars, and over 300 R&D elite team members.We set up industrial technology research institute, postdoctoral workstation and Haizhi workstation. We have been approved as a new high-end research and development institution, key laboratory, engineering research center, engineering technology research center, regional cell preparation center and other platform construction units in Chongqing. We have built an 18,000-square-meter upstream and downstream integrated platform covering the development of cellular drugs, which can support the pre-clinical research, technological research and development, analytical testing and technological production of drugs IND and NDA.

       As a technology innovation enterprise, relying on strong research and development and transformation capabilities, we have  continuously achieved breakthrough innovations in core technologies and cutting-edge fields.With more than 20 years experience in the field,our R&D team has acquired core technologies of cell therapy and mastered the key technologies of CAR-T cell therapy.We have applied for 38 patents, and carried out patent layout in developed countries and regions. We currently focus on the application of more than 10 CAR-T research and development pipeline for leukemia, lymphoma, myeloma, gastrointestinal cancer, lung cancer, liver cancer, breast cancer, and pancreatic cancer. We obtained 4 Class I biological CAR-T new drugs and 9 indications of implied license. Our registered clinical trials are progressing smoothly and have achieved excellent clinical data, realizing the first breakthrough in CAR-T technology for the treatment of solid tumors such as colorectal cancer and kidney cancer.


Events
2015
2017
2018
2020
2021
2023
2015
Sep.

The technical team signed a cooperation agreement with Zhirui Investment.

2016
Jan.

Chongqing Precision Biotech Co., Ltd. established.

Oct.

1st phase of 6,652 square meters R&D transformation base was started.

2017
May

pCAR-19B product starts clinical IIT research.

2018
Feb.

pCAR-19B was accepted for clinical application of Class I New drugs.

Oct.

2nd phase of 15,700 square meters of R&D transformation base started construction.

2019
Feb.

The first indication of pCAR-19B was approved.

Oct.

The first case of dual-target CAR-T IIT study was enrolled.
CAR-T cell preparation workshop started.

Nov.

Start pCAR-19B registration clinical trial for children and adolescents with acute lymphoblastic leukemia.

Dec.

Start clinical lIT study of CEA target CAR-T in solid tumor projec.

2020
May

Clinical implied license for two new indications of pCAR-19B was approved.

Oct.

Start the registered clinical trial of pCAR-19B cell therapy for adult (22-70 years old) B ALL.

Dec.

Class I New drug Clinical implied license of C-4-29 was approved.

2021
Jan.

The first IIT patient of CAR-NK was enrolled.

Mar.

The first IIT patient in CD19+CD22 dual-CAR-T project was enrolled.

May

The first clinical patient with AML IIT was enrolled.
C-4-29 Clinical start-up; Phase I clinical start-up of MM indications.

June

Signed an investment agreement with Chongqing Science City for the third phase of 100,000 ㎡ regional cell preparation base.

July

C-13-60 solid tumor project IIT started.

Sep.

Complete phase I clinical of pCAR-19B ALL in children. C-4-29 RCC obtained clinical approval.

Dec.

Complete phase I clinical of pCAR-19B adult ALL.

2022
Dec

Our self-developed C-13-60 cell preparation has been approved by NMPA for clinical trials

Nov

The number of our patent applications exceeded 100.

June

Chongqing Precision Biotech reported data from PrimeCAR-T platform at the American Society for Clinical Oncology (ASCO) Annual Meeting in 2022

Feb.

Initiate Phase II registered clinical trial of pCAR-19B cell autotransfusion preparation for the treatment of children and adolescents with relapsed/refractory B-cell acute lymphoblastic leukemia (B-ALL).

2023
Jan

Approved Drug Production License for CAR-T cell therapy products

Chongqing High-tech Enterprise

Postdoctoral workstation

New high-end Research and Development Institution

Demonstration Alliance for Technological Innovation of Precision Medical Industry

Regional Cell Preparation Center

Chongqing Engineering Research Center for Genes and Cells

Chongqing Cell Therapy Engineering Research Center

Chongqing Key Laboratory of Gene and Cell Therapy

Chongqing Key Laboratory of Industry and Information Technology for Tumor Immunotherapy