ABOUT US

Introduction

Overview

Chongqing Precision Biotech Co., Ltd. (hereinafter referred to as the “Company”) was founded in 2016 as a high-tech enterprise established by a technical team led by Professor Qian Cheng, a renowned scientist in precision medicine. Taking gene editing and synthetic biology technologies as its core technological foundation, the Company focuses on the development and application of gene and cell therapeutics. It has grown into one of China’s leading enterprises in the CAR-T/NK field and is committed to becoming a global, innovative, and pioneering biopharmaceutical company.

The Company has established R&D collaboration and expert exchange mechanisms with 7 overseas institutions and 19 domestic universities, bringing together more than 20 experts and scholars and a high-caliber R&D team of over 300 professionals. It has established an Industrial Technology Research Institute, a Postdoctoral Research Workstation, and an Overseas Talent Workstation, and has been accredited as a Chongqing New High-end R&D Institution, Technology Innovation Center, Key Laboratory, and Engineering Research Center, among other innovation platforms.

As an enterprise driven by cutting-edge technological innovation, the Company masters key technologies in the cell therapy field, with more than 200 invention patents filed and patent portfolios deployed across developed countries and regions. The Company has advanced more than 10 CAR-T product pipelines targeting leukemia, lymphoma, multiple myeloma, gastrointestinal cancer, lung cancer, liver cancer, breast cancer, pancreatic cancer and other malignancies. To date, the Company has obtained four Class I biological new drug approvals for CAR-T cells and ten implied licenses for indications, making it the most innovative enterprise with the largest number of approved registered clinical pipelines in China. 

Its registered clinical trials are progressing smoothly and have achieved excellent efficacy data. The Company’s CAR-T therapy for pediatric leukemia became China’s first approved CAR-T drug product. Meanwhile, its CAR-T therapies for solid tumors such as colorectal cancer and gastric cancer achieved the first registered clinical approvals in China in these indications, placing the Company at the forefront of global clinical development and drug registration. At the same time, the Company is actively advancing cutting-edge technologies including point-of-care manufacturing, in vivo CAR-T, oncolytic viruses, gene therapeutics, and mRNA technologies.

Currently, the Company has built a 18,000-square-meter fully integrated platform covering the entire upstream and downstream of cell therapeutics development, and has been granted the first CAR-T Drug Manufacturing License in Western China, making it one of only a few companies in China holding such a qualification.The Company is also establishing a regional cell manufacturing center in the core area of Chongqing Western Science City. Included in the National Development and Reform Commission (NDRC)’s national “Major Strategic Projects” program and supported by dedicated policy and funding initiatives, the project is expected to deliver an annual production capacity of 100,000 batches of cell products and intermediates. Based on the Chongqing manufacturing base, the facility will support the cell preparation needs of the Company’s clinical centers nationwide. By 2028, the Company aims to launch 3-5 Class I national CAR-T drugs and achieve sales revenue exceeding RMB 10 billion.

Events
2015
2017
2018
2020
2021
2023
2024
2026
2015
Sep.

The technical team signed a cooperation agreement with Zhirui Investment.

2016
Jan.

Chongqing Precision Biotech Co., Ltd. established.

Oct.

1st phase of 6,652 square meters R&D transformation base was started.

2017
May.

pCAR-19B product starts clinical IIT research.

2018
Feb.

pCAR-19B was accepted for clinical application of Class I New drugs.

Oct.

2nd phase of 15,700 square meters of R&D transformation base started construction.

2019
Feb.

The first indication of pCAR-19B was approved.

Oct.

The first case of dual-target CAR-T IIT study was enrolled.
CAR-T cell preparation workshop started.

Nov.

Start pCAR-19B registration clinical trial for children and adolescents with acute lymphoblastic leukemia.

Dec.

Start clinical lIT study of CEA target CAR-T in solid tumor projec.

2020
May.

Clinical implied license for two new indications of pCAR-19B was approved.

Oct.

Start the registered clinical trial of pCAR-19B cell therapy for adult (22-70 years old) B ALL.

Dec.

Class I New drug Clinical implied license of C-4-29 was approved.

2021
Jan.

The first IIT patient of CAR-NK was enrolled.

Mar.

The first IIT patient in CD19+CD22 dual-CAR-T project was enrolled.

May.

The first clinical patient with AML IIT was enrolled.
C-4-29 Clinical start-up; Phase I clinical start-up of MM indications.

Jun.

Signed an investment agreement with Chongqing Science City for the third phase of 100,000 ㎡ regional cell preparation base.

Jul.

C-13-60 solid tumor project IIT started.

Sep.

Complete phase I clinical of pCAR-19B ALL in children. C-4-29 RCC obtained clinical approval.

Dec.

Complete phase I clinical of pCAR-19B adult ALL.

2022
Feb.

Initiate Phase II registered clinical trial of pCAR-19B cell autotransfusion preparation for the treatment of children and adolescents with relapsed/refractory B-cell acute lymphoblastic leukemia (B-ALL).

Jun.

Chongqing Precision Biotech reported data from PrimeCAR-T platform at the American Society for Clinical Oncology (ASCO) Annual Meeting in 2022

Nov.

The number of our patent applications exceeded 100.

Dec.

Our self-developed C-13-60 cell preparation has been approved by NMPA for clinical trials

2023
Jan.

Approved Drug Production License for CAR-T cell therapy products

Jun.

Three abstracts of clinical and preclinical research results of Precision Biotech were published in ASCO official website.

Jul.

MC-1-50 received IND application acceptance by CDE.

Aug.

C-13-60 entered Phase I registration clinical trial.

Sep.

pCAR-19B phase II clinical trials for children's ALL was completed.

Oct.

The implied license of Class I biological new drugs for MC-1-50 was granted.

Nov.

pCAR-19B, as the first CAR-T product for the treatment of childhood leukemia in China was approved to be included in the list of "Breakthrough Therapy Varieties".

Dec.

MC-1-50 cell preparation and C-13-60 cell preparation were successively approved for the second indication.

2024
Jan.

The cell drug HVCT-RM traceability system of Precision Biotech was officially put into operation.

Jun.

pCAR-19B cell autologous infusion preparation (Priscabtagene Autoleucel Injection) was proposed to be included in the "Priority Evaluation Variety" for the treatment of CD19-positive relapsed or refractory B-cell acute lymphoblastic leukemia patients aged 3-21 years.

Jun.

Chongqing Precision Biotech announced its clinical breakthrough in solid tumors at the 2024 American Society of Clinical Oncology (ASCO) Annual Meeting .

Jul.

National Medical Products Administration (NMPA) has accepted the New Drug Application for our self-developed National Class I biological new drug pCAR-19B cell autologous infusion preparation (Priscabtagene Autoleucel Injection).

2025
2026

Technology Center of Enterprises of Chongqing

Chongqing High-tech Enterprise

Postdoctoral workstation

New high-end Research and Development Institution

Demonstration Alliance for Technological Innovation of Precision Medical Industry

Regional Cell Preparation Center

Chongqing Engineering Research Center for Genes and Cells

Chongqing Cell Therapy Engineering Research Center

Chongqing Key Laboratory of Gene and Cell Therapy

Chongqing Key Laboratory of Industry and Information Technology for Tumor Immunotherapy

Chongqing Cell and Gene Technology Innovation Center